BDBM50245908 CHEMBL518822::N3-(2,6-dimethylphenyl)-1-(2-morpholinoethyl)-N6-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine

SMILES: Cc1cccc(C)c1Nc1nn(CCN2CCOCC2)c2nc(Nc3ccccc3)ncc12

InChI Key: InChIKey=LDAWSYOWVKTXAN-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine kinase non-receptor protein 2 (Homo sapiens (Human))	BDBM50245908 (CHEMBL518822 | N3-(2,6-dimethylphenyl)-1-(2-morpho...) Show SMILES Cc1cccc(C)c1Nc1nn(CCN2CCOCC2)c2nc(Nc3ccccc3)ncc12 Show InChI InChI=1S/C25H29N7O/c1-18-7-6-8-19(2)22(18)28-23-21-17-26-25(27-20-9-4-3-5-10-20)29-24(21)32(30-23)12-11-31-13-15-33-16-14-31/h3-10,17H,11-16H2,1-2H3,(H,28,30)(H,26,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of histidine-tagged ACK1 (amino acids 117 to 489) (unknown origin) expressed in SF9 cells				Bioorg Med Chem Lett 18: 6352-6 (2008) Article DOI: 10.1016/j.bmcl.2008.10.092 BindingDB Entry DOI: 10.7270/Q2B56JKZ
					More data for this Ligand-Target Pair
Tyrosine kinase non-receptor protein 2 (Homo sapiens (Human))	BDBM50245908 (CHEMBL518822 | N3-(2,6-dimethylphenyl)-1-(2-morpho...) Show SMILES Cc1cccc(C)c1Nc1nn(CCN2CCOCC2)c2nc(Nc3ccccc3)ncc12 Show InChI InChI=1S/C25H29N7O/c1-18-7-6-8-19(2)22(18)28-23-21-17-26-25(27-20-9-4-3-5-10-20)29-24(21)32(30-23)12-11-31-13-15-33-16-14-31/h3-10,17H,11-16H2,1-2H3,(H,28,30)(H,26,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of flag-tagged ACK1 (unknown origin) autophosphorylation expressed in human 293 cells				Bioorg Med Chem Lett 18: 6352-6 (2008) Article DOI: 10.1016/j.bmcl.2008.10.092 BindingDB Entry DOI: 10.7270/Q2B56JKZ
					More data for this Ligand-Target Pair