BDBM50245912 ((S)-3-(cyclopropylamino)pyrrolidin-1-yl)(4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-ylamino)phenyl)methanone::CHEMBL460086

SMILES: CC(C)n1c(C)ncc1-c1ccnc(Nc2ccc(cc2)C(=O)N2CC[C@@H](C2)NC2CC2)n1

InChI Key: InChIKey=RWVYOYMRKMXRCK-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50245912 (((S)-3-(cyclopropylamino)pyrrolidin-1-yl)(4-(4-(1-...) Show SMILES CC(C)n1c(C)ncc1-c1ccnc(Nc2ccc(cc2)C(=O)N2CC[C@@H](C2)NC2CC2)n1 |r| Show InChI InChI=1S/C25H31N7O/c1-16(2)32-17(3)27-14-23(32)22-10-12-26-25(30-22)29-20-6-4-18(5-7-20)24(33)31-13-11-21(15-31)28-19-8-9-19/h4-7,10,12,14,16,19,21,28H,8-9,11,13,15H2,1-3H3,(H,26,29,30)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of CDK1 (unknown origin)				Bioorg Med Chem Lett 18: 6369-73 (2008) Article DOI: 10.1016/j.bmcl.2008.10.102 BindingDB Entry DOI: 10.7270/Q2XW4JNM
					More data for this Ligand-Target Pair