null

SMILES: Fc1ccc(cc1)C1CN(C(=O)O1)c1cccc(F)c1

InChI Key: InChIKey=PYKKXYBBIFUYHQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246022   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA (8-3)-desaturase (Rattus norvegicus)	BDBM50246022 (CHEMBL4080025) Show SMILES Fc1ccc(cc1)C1CN(C(=O)O1)c1cccc(F)c1 Show InChI InChI=1S/C15H11F2NO2/c16-11-6-4-10(5-7-11)14-9-18(15(19)20-14)13-3-1-2-12(17)8-13/h1-8,14H,9H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...				J Med Chem 60: 8963-8981 (2017) Article DOI: 10.1021/acs.jmedchem.7b01210 BindingDB Entry DOI: 10.7270/Q23N25S7
					More data for this Ligand-Target Pair
Acyl-CoA (8-3)-desaturase (Homo sapiens (Human))	BDBM50246022 (CHEMBL4080025) Show SMILES Fc1ccc(cc1)C1CN(C(=O)O1)c1cccc(F)c1 Show InChI InChI=1S/C15H11F2NO2/c16-11-6-4-10(5-7-11)14-9-18(15(19)20-14)13-3-1-2-12(17)8-13/h1-8,14H,9H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...				J Med Chem 60: 8963-8981 (2017) Article DOI: 10.1021/acs.jmedchem.7b01210 BindingDB Entry DOI: 10.7270/Q23N25S7
					More data for this Ligand-Target Pair