BDBM50246023 CHEMBL4060775

SMILES: COc1cccc(c1)N1CC(OC1=O)c1ccc(F)cc1

InChI Key: InChIKey=WSFCYHWLRWAZNS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA (8-3)-desaturase (Rattus norvegicus)	BDBM50246023 (CHEMBL4060775) Show SMILES COc1cccc(c1)N1CC(OC1=O)c1ccc(F)cc1 Show InChI InChI=1S/C16H14FNO3/c1-20-14-4-2-3-13(9-14)18-10-15(21-16(18)19)11-5-7-12(17)8-6-11/h2-9,15H,10H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...				J Med Chem 60: 8963-8981 (2017) Article DOI: 10.1021/acs.jmedchem.7b01210 BindingDB Entry DOI: 10.7270/Q23N25S7
					More data for this Ligand-Target Pair
Acyl-CoA (8-3)-desaturase (Homo sapiens (Human))	BDBM50246023 (CHEMBL4060775) Show SMILES COc1cccc(c1)N1CC(OC1=O)c1ccc(F)cc1 Show InChI InChI=1S/C16H14FNO3/c1-20-14-4-2-3-13(9-14)18-10-15(21-16(18)19)11-5-7-12(17)8-6-11/h2-9,15H,10H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...				J Med Chem 60: 8963-8981 (2017) Article DOI: 10.1021/acs.jmedchem.7b01210 BindingDB Entry DOI: 10.7270/Q23N25S7
					More data for this Ligand-Target Pair