BDBM50246218 2-(3-(2,6-dichlorophenylamino)-6-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-morpholinoethanone::CHEMBL519916

SMILES: Clc1cccc(Cl)c1Nc1nn(CC(=O)N2CCOCC2)c2nc(Nc3ccccc3)ncc12

InChI Key: InChIKey=SJUHXKMDZJBXRI-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246218   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine kinase non-receptor protein 2 (Homo sapiens (Human))	BDBM50246218 (2-(3-(2,6-dichlorophenylamino)-6-(phenylamino)-1H-...) Show SMILES Clc1cccc(Cl)c1Nc1nn(CC(=O)N2CCOCC2)c2nc(Nc3ccccc3)ncc12 Show InChI InChI=1S/C23H21Cl2N7O2/c24-17-7-4-8-18(25)20(17)28-21-16-13-26-23(27-15-5-2-1-3-6-15)29-22(16)32(30-21)14-19(33)31-9-11-34-12-10-31/h1-8,13H,9-12,14H2,(H,28,30)(H,26,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of histidine-tagged ACK1 (amino acids 117 to 489) (unknown origin) expressed in SF9 cells				Bioorg Med Chem Lett 18: 6352-6 (2008) Article DOI: 10.1016/j.bmcl.2008.10.092 BindingDB Entry DOI: 10.7270/Q2B56JKZ
					More data for this Ligand-Target Pair
Tyrosine kinase non-receptor protein 2 (Homo sapiens (Human))	BDBM50246218 (2-(3-(2,6-dichlorophenylamino)-6-(phenylamino)-1H-...) Show SMILES Clc1cccc(Cl)c1Nc1nn(CC(=O)N2CCOCC2)c2nc(Nc3ccccc3)ncc12 Show InChI InChI=1S/C23H21Cl2N7O2/c24-17-7-4-8-18(25)20(17)28-21-16-13-26-23(27-15-5-2-1-3-6-15)29-22(16)32(30-21)14-19(33)31-9-11-34-12-10-31/h1-8,13H,9-12,14H2,(H,28,30)(H,26,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of flag-tagged ACK1 (unknown origin) autophosphorylation expressed in human 293 cells				Bioorg Med Chem Lett 18: 6352-6 (2008) Article DOI: 10.1016/j.bmcl.2008.10.092 BindingDB Entry DOI: 10.7270/Q2B56JKZ
					More data for this Ligand-Target Pair