Found 11 hits for monomerid = 50246600 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50246600
(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)Show InChI InChI=1S/C11H14N2O7S/c1-20-8-2-4-9(5-3-8)21(18,19)13(7-11(15)16)6-10(14)12-17/h2-5,17H,6-7H2,1H3,(H,12,14)(H,15,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 322 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Superior Técnico
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 51: 7968-79 (2008)
Article DOI: 10.1021/jm800964f BindingDB Entry DOI: 10.7270/Q2XK8FDN |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-14 (MMP14)
(Homo sapiens (Human)) | BDBM50246600
(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)Show InChI InChI=1S/C11H14N2O7S/c1-20-8-2-4-9(5-3-8)21(18,19)13(7-11(15)16)6-10(14)12-17/h2-5,17H,6-7H2,1H3,(H,12,14)(H,15,16) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Superior Técnico
Curated by ChEMBL
| Assay Description Inhibition of MMP14 |
J Med Chem 51: 7968-79 (2008)
Article DOI: 10.1021/jm800964f BindingDB Entry DOI: 10.7270/Q2XK8FDN |
More data for this Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50246600
(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)Show InChI InChI=1S/C11H14N2O7S/c1-20-8-2-4-9(5-3-8)21(18,19)13(7-11(15)16)6-10(14)12-17/h2-5,17H,6-7H2,1H3,(H,12,14)(H,15,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Superior Técnico
Curated by ChEMBL
| Assay Description Inhibition of MMP1 |
J Med Chem 51: 7968-79 (2008)
Article DOI: 10.1021/jm800964f BindingDB Entry DOI: 10.7270/Q2XK8FDN |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50246600
(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)Show InChI InChI=1S/C11H14N2O7S/c1-20-8-2-4-9(5-3-8)21(18,19)13(7-11(15)16)6-10(14)12-17/h2-5,17H,6-7H2,1H3,(H,12,14)(H,15,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 193 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Superior Técnico
Curated by ChEMBL
| Assay Description Inhibition of human recombinant MMP2 transfected in mouse melanoma cells |
J Med Chem 51: 7968-79 (2008)
Article DOI: 10.1021/jm800964f BindingDB Entry DOI: 10.7270/Q2XK8FDN |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50246600
(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)Show InChI InChI=1S/C11H14N2O7S/c1-20-8-2-4-9(5-3-8)21(18,19)13(7-11(15)16)6-10(14)12-17/h2-5,17H,6-7H2,1H3,(H,12,14)(H,15,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Superior Técnico
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 51: 7968-79 (2008)
Article DOI: 10.1021/jm800964f BindingDB Entry DOI: 10.7270/Q2XK8FDN |
More data for this Ligand-Target Pair | |
Pseudolysin
(Pseudomonas aeruginosa) | BDBM50246600
(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)Show InChI InChI=1S/C11H14N2O7S/c1-20-8-2-4-9(5-3-8)21(18,19)13(7-11(15)16)6-10(14)12-17/h2-5,17H,6-7H2,1H3,(H,12,14)(H,15,16) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.69E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
UiT - The Arctic University of Norway
Curated by ChEMBL
| Assay Description Inhibition of Pseudomonas aeruginosa pseudolysin using Abz-Ala-Gly-Leu-Ala-p-nitrobenzylamide as substrate after 15 mins |
Eur J Med Chem 89: 340-8 (2015)
Article DOI: 10.1016/j.ejmech.2014.10.009 BindingDB Entry DOI: 10.7270/Q21Z47DC |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase 16
(Homo sapiens (Human)) | BDBM50246600
(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)Show InChI InChI=1S/C11H14N2O7S/c1-20-8-2-4-9(5-3-8)21(18,19)13(7-11(15)16)6-10(14)12-17/h2-5,17H,6-7H2,1H3,(H,12,14)(H,15,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 996 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Superior Técnico
Curated by ChEMBL
| Assay Description Inhibition of MMP16 |
J Med Chem 51: 7968-79 (2008)
Article DOI: 10.1021/jm800964f BindingDB Entry DOI: 10.7270/Q2XK8FDN |
More data for this Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50246600
(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)Show InChI InChI=1S/C11H14N2O7S/c1-20-8-2-4-9(5-3-8)21(18,19)13(7-11(15)16)6-10(14)12-17/h2-5,17H,6-7H2,1H3,(H,12,14)(H,15,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.45E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067 BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this Ligand-Target Pair | |
Meprin A subunit beta
(Homo sapiens) | BDBM50246600
(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)Show InChI InChI=1S/C11H14N2O7S/c1-20-8-2-4-9(5-3-8)21(18,19)13(7-11(15)16)6-10(14)12-17/h2-5,17H,6-7H2,1H3,(H,12,14)(H,15,16) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Fraunhofer Institute for Cell Therapy and Immunology IZI
Curated by ChEMBL
| Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay |
Bioorg Med Chem Lett 27: 2428-2431 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0 |
More data for this Ligand-Target Pair | |
Pseudolysin
(Pseudomonas aeruginosa) | BDBM50246600
(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)Show InChI InChI=1S/C11H14N2O7S/c1-20-8-2-4-9(5-3-8)21(18,19)13(7-11(15)16)6-10(14)12-17/h2-5,17H,6-7H2,1H3,(H,12,14)(H,15,16) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.53E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
UiT - The Arctic University of Norway
Curated by ChEMBL
| Assay Description Inhibition of Pseudomonas aeruginosa pseudolysin using Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys-(Dnp)-OH as substrate after 1 hr by fluorescence assay... |
Eur J Med Chem 89: 340-8 (2015)
Article DOI: 10.1016/j.ejmech.2014.10.009 BindingDB Entry DOI: 10.7270/Q21Z47DC |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50246600
(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)Show InChI InChI=1S/C11H14N2O7S/c1-20-8-2-4-9(5-3-8)21(18,19)13(7-11(15)16)6-10(14)12-17/h2-5,17H,6-7H2,1H3,(H,12,14)(H,15,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 213 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Superior Técnico
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 51: 7968-79 (2008)
Article DOI: 10.1021/jm800964f BindingDB Entry DOI: 10.7270/Q2XK8FDN |
More data for this Ligand-Target Pair | |