BDBM50246604 6,7-dimethoxy-9-methyl-4-phenyl-2H-pyrido[3,4-b]indol-1(9H)-one::CHEMBL515871

SMILES: COc1cc2n(C)c3c(c(c[nH]c3=O)-c3ccccc3)c2cc1OC

InChI Key: InChIKey=IJYDBAXDVRHBCC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50246604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50246604 (6,7-dimethoxy-9-methyl-4-phenyl-2H-pyrido[3,4-b]in...) Show SMILES COc1cc2n(C)c3c(c(c[nH]c3=O)-c3ccccc3)c2cc1OC Show InChI InChI=1S/C20H18N2O3/c1-22-15-10-17(25-3)16(24-2)9-13(15)18-14(11-21-20(23)19(18)22)12-7-5-4-6-8-12/h4-11H,1-3H3,(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Milano Curated by ChEMBL					Assay Description Inhibition of recombinant RET active protein (unknown origin) by immunoblotting				J Med Chem 51: 7777-87 (2008) Article DOI: 10.1021/jm8007823 BindingDB Entry DOI: 10.7270/Q2DN44X5
					More data for this Ligand-Target Pair