BDBM50247036 1-(4-chlorooxazol-2-yl)-7-phenylheptan-1-one::CHEMBL462432
SMILES: Clc1coc(n1)C(=O)CCCCCCc1ccccc1
InChI Key: InChIKey=HEJGWGQTJYVGGY-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat)) | BDBM50247036 (1-(4-chlorooxazol-2-yl)-7-phenylheptan-1-one | CHE...) | PDB MMDB B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of rat FAAH | Bioorg Med Chem Lett 18: 5842-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.084 BindingDB Entry DOI: 10.7270/Q2DN44V8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sn1-specific diacylglycerol lipase alpha (Homo sapiens (Human)) | BDBM50247036 (1-(4-chlorooxazol-2-yl)-7-phenylheptan-1-one | CHE...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assay | J Med Chem 58: 9742-53 (2015) Article DOI: 10.1021/acs.jmedchem.5b01627 BindingDB Entry DOI: 10.7270/Q2D50QZ9 | |||||||||||
More data for this Ligand-Target Pair |