BDBM50247136 2-(7-phenylheptanoyl)oxazole-4-carbonitrile::CHEMBL462423

SMILES: O=C(CCCCCCc1ccccc1)c1nc(co1)C#N

InChI Key: InChIKey=IGDLMZPDBOKHRJ-UHFFFAOYSA-N

Data: 1 KI  4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50247136   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50247136 (2-(7-phenylheptanoyl)oxazole-4-carbonitrile | CHEM...) Show SMILES O=C(CCCCCCc1ccccc1)c1nc(co1)C#N Show InChI InChI=1S/C17H18N2O2/c18-12-15-13-21-17(19-15)16(20)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,13H,1-2,4,7-8,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat FAAH				Bioorg Med Chem Lett 18: 5842-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.084 BindingDB Entry DOI: 10.7270/Q2DN44V8
					More data for this Ligand-Target Pair
Sn1-specific diacylglycerol lipase alpha (Homo sapiens (Human))	BDBM50247136 (2-(7-phenylheptanoyl)oxazole-4-carbonitrile | CHEM...) Show SMILES O=C(CCCCCCc1ccccc1)c1nc(co1)C#N Show InChI InChI=1S/C17H18N2O2/c18-12-15-13-21-17(19-15)16(20)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,13H,1-2,4,7-8,11H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	575	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assay				J Med Chem 58: 9742-53 (2015) Article DOI: 10.1021/acs.jmedchem.5b01627 BindingDB Entry DOI: 10.7270/Q2D50QZ9
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50247136 (2-(7-phenylheptanoyl)oxazole-4-carbonitrile | CHEM...) Show SMILES O=C(CCCCCCc1ccccc1)c1nc(co1)C#N Show InChI InChI=1S/C17H18N2O2/c18-12-15-13-21-17(19-15)16(20)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,13H,1-2,4,7-8,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat FAAH				Bioorg Med Chem Lett 18: 5842-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.084 BindingDB Entry DOI: 10.7270/Q2DN44V8
					More data for this Ligand-Target Pair
Neutral cholesterol ester hydrolase 1 (Homo sapiens (Human))	BDBM50247136 (2-(7-phenylheptanoyl)oxazole-4-carbonitrile | CHEM...) Show SMILES O=C(CCCCCCc1ccccc1)c1nc(co1)C#N Show InChI InChI=1S/C17H18N2O2/c18-12-15-13-21-17(19-15)16(20)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,13H,1-2,4,7-8,11H2	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of KIAA1363 (unknown origin)				Bioorg Med Chem Lett 18: 5842-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.084 BindingDB Entry DOI: 10.7270/Q2DN44V8
					More data for this Ligand-Target Pair
Acyl-CoA: cholesterol acyltransferase (ACAT) (Homo sapiens (Human))	BDBM50247136 (2-(7-phenylheptanoyl)oxazole-4-carbonitrile | CHEM...) Show SMILES O=C(CCCCCCc1ccccc1)c1nc(co1)C#N Show InChI InChI=1S/C17H18N2O2/c18-12-15-13-21-17(19-15)16(20)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,13H,1-2,4,7-8,11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of TGH (unknown origin)				Bioorg Med Chem Lett 18: 5842-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.084 BindingDB Entry DOI: 10.7270/Q2DN44V8
					More data for this Ligand-Target Pair