BDBM50247372 8-Ethyl-9-oxo-8,9-dihydro-6-thiazolo[5,4-f]quinazoline-2-carboximidic acid ethyl ester::CHEMBL506669

SMILES: CCOC(=N)c1nc2ccc3ncn(CC)c(=O)c3c2s1

InChI Key: InChIKey=KXPLADSXXPSEQO-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50247372   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50247372 (8-Ethyl-9-oxo-8,9-dihydro-6-thiazolo[5,4-f]quinazo...) Show SMILES CCOC(=N)c1nc2ccc3ncn(CC)c(=O)c3c2s1 Show InChI InChI=1S/C14H14N4O2S/c1-3-18-7-16-8-5-6-9-11(10(8)14(18)19)21-13(17-9)12(15)20-4-2/h5-7,15H,3-4H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université de Nantes Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclinB (unknown origin)				Eur J Med Chem 43: 1469-77 (2008) Article DOI: 10.1016/j.ejmech.2007.09.020 BindingDB Entry DOI: 10.7270/Q24M9495
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50247372 (8-Ethyl-9-oxo-8,9-dihydro-6-thiazolo[5,4-f]quinazo...) Show SMILES CCOC(=N)c1nc2ccc3ncn(CC)c(=O)c3c2s1 Show InChI InChI=1S/C14H14N4O2S/c1-3-18-7-16-8-5-6-9-11(10(8)14(18)19)21-13(17-9)12(15)20-4-2/h5-7,15H,3-4H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université de Nantes Curated by ChEMBL					Assay Description Inhibition of CDK1 (unknown origin)				Eur J Med Chem 43: 1469-77 (2008) Article DOI: 10.1016/j.ejmech.2007.09.020 BindingDB Entry DOI: 10.7270/Q24M9495
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 (Homo sapiens (Human))	BDBM50247372 (8-Ethyl-9-oxo-8,9-dihydro-6-thiazolo[5,4-f]quinazo...) Show SMILES CCOC(=N)c1nc2ccc3ncn(CC)c(=O)c3c2s1 Show InChI InChI=1S/C14H14N4O2S/c1-3-18-7-16-8-5-6-9-11(10(8)14(18)19)21-13(17-9)12(15)20-4-2/h5-7,15H,3-4H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Nantes Curated by ChEMBL					Assay Description Inhibition of GSK3alpha/beta (unknown origin)				Eur J Med Chem 43: 1469-77 (2008) Article DOI: 10.1016/j.ejmech.2007.09.020 BindingDB Entry DOI: 10.7270/Q24M9495
					More data for this Ligand-Target Pair