BDBM50247375 CHEMBL4074611

SMILES: O=C(CNC(=O)Nc1ccc2cnccc2c1)NC1CC1

InChI Key: InChIKey=JPRQOBHIEOKSNW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 3 (Homo sapiens)	BDBM50247375 (CHEMBL4074611) Show SMILES O=C(CNC(=O)Nc1ccc2cnccc2c1)NC1CC1 Show InChI InChI=1S/C15H16N4O2/c20-14(18-12-3-4-12)9-17-15(21)19-13-2-1-11-8-16-6-5-10(11)7-13/h1-2,5-8,12H,3-4,9H2,(H,18,20)(H2,17,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of PRMT3 (unknown origin) using C-terminally biotinylated histone H4 as substrate in presence of [3H]S-adenosylmethionine by scintillation...				J Med Chem 61: 1204-1217 (2018) Article DOI: 10.1021/acs.jmedchem.7b01674 BindingDB Entry DOI: 10.7270/Q24J0HK6
					More data for this Ligand-Target Pair