BDBM50247381 CHEMBL4079503

SMILES: Fc1cc2cc(NC(=O)NCC(=O)N3CCCC3)ccc2cn1

InChI Key: InChIKey=HPJFXECZFPAPBC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247381   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 3 (Homo sapiens)	BDBM50247381 (CHEMBL4079503) Show SMILES Fc1cc2cc(NC(=O)NCC(=O)N3CCCC3)ccc2cn1 Show InChI InChI=1S/C16H17FN4O2/c17-14-8-12-7-13(4-3-11(12)9-18-14)20-16(23)19-10-15(22)21-5-1-2-6-21/h3-4,7-9H,1-2,5-6,10H2,(H2,19,20,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of PRMT3 (unknown origin) using C-terminally biotinylated histone H4 as substrate in presence of [3H]S-adenosylmethionine by scintillation...				J Med Chem 61: 1204-1217 (2018) Article DOI: 10.1021/acs.jmedchem.7b01674 BindingDB Entry DOI: 10.7270/Q24J0HK6
					More data for this Ligand-Target Pair