BDBM50247392 8-Ethyl-9-oxo-8,9-dihydro-thiazolo[5,4-f]quinazoline-2-carboximidic acid butyl ester::CHEMBL453131

SMILES: CCCCOC(=N)c1nc2ccc3ncn(CC)c(=O)c3c2s1

InChI Key: InChIKey=FJMPCGCOGLTHPC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50247392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 (Homo sapiens (Human))	BDBM50247392 (8-Ethyl-9-oxo-8,9-dihydro-thiazolo[5,4-f]quinazoli...) Show SMILES CCCCOC(=N)c1nc2ccc3ncn(CC)c(=O)c3c2s1 Show InChI InChI=1S/C16H18N4O2S/c1-3-5-8-22-14(17)15-19-11-7-6-10-12(13(11)23-15)16(21)20(4-2)9-18-10/h6-7,9,17H,3-5,8H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Université de Nantes Curated by ChEMBL					Assay Description Inhibition of GSK3alpha/beta (unknown origin)				Eur J Med Chem 43: 1469-77 (2008) Article DOI: 10.1016/j.ejmech.2007.09.020 BindingDB Entry DOI: 10.7270/Q24M9495
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50247392 (8-Ethyl-9-oxo-8,9-dihydro-thiazolo[5,4-f]quinazoli...) Show SMILES CCCCOC(=N)c1nc2ccc3ncn(CC)c(=O)c3c2s1 Show InChI InChI=1S/C16H18N4O2S/c1-3-5-8-22-14(17)15-19-11-7-6-10-12(13(11)23-15)16(21)20(4-2)9-18-10/h6-7,9,17H,3-5,8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Nantes Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclinB (unknown origin)				Eur J Med Chem 43: 1469-77 (2008) Article DOI: 10.1016/j.ejmech.2007.09.020 BindingDB Entry DOI: 10.7270/Q24M9495
					More data for this Ligand-Target Pair