BDBM50247409 CHEMBL4093660

SMILES: Oc1ccc2ccccc2c1\C=N\NS(=O)(=O)Cc1ccccc1

InChI Key: InChIKey=LPNCCARRTTVROX-XDHOZWIPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribonucleoside-diphosphate reductase large subunit (Homo sapiens (Human))	BDBM50247409 (CHEMBL4093660) Show SMILES Oc1ccc2ccccc2c1\C=N\NS(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C18H16N2O3S/c21-18-11-10-15-8-4-5-9-16(15)17(18)12-19-20-24(22,23)13-14-6-2-1-3-7-14/h1-12,20-21H,13H2/b19-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.31E+5	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by ChEMBL					Assay Description Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...				J Med Chem 61: 666-680 (2018) BindingDB Entry DOI: 10.7270/Q2W098CB
					More data for this Ligand-Target Pair