BDBM50247412 CHEMBL4074537

SMILES: CN(C)c1ccc(\C=N\N=C\c2c(O)ccc3ccccc23)cc1

InChI Key: InChIKey=TTXCKLGUAAMDHU-JFMUQQRKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247412   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribonucleoside-diphosphate reductase large subunit (Homo sapiens (Human))	BDBM50247412 (CHEMBL4074537) Show SMILES CN(C)c1ccc(\C=N\N=C\c2c(O)ccc3ccccc23)cc1 Show InChI InChI=1S/C20H19N3O/c1-23(2)17-10-7-15(8-11-17)13-21-22-14-19-18-6-4-3-5-16(18)9-12-20(19)24/h3-14,24H,1-2H3/b21-13+,22-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by ChEMBL					Assay Description Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...				J Med Chem 61: 666-680 (2018) BindingDB Entry DOI: 10.7270/Q2W098CB
					More data for this Ligand-Target Pair