BDBM50247417 8-Isopropyl-9-oxo-8,9-dihydro-thiazolo[5,4-f]quinazoline-2-carboximidic acid butyl ester::CHEMBL453128

SMILES: CCCCOC(=N)c1nc2ccc3ncn(C(C)C)c(=O)c3c2s1

InChI Key: InChIKey=YYWGDJIEQNZXDR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50247417   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 (Homo sapiens (Human))	BDBM50247417 (8-Isopropyl-9-oxo-8,9-dihydro-thiazolo[5,4-f]quina...) Show SMILES CCCCOC(=N)c1nc2ccc3ncn(C(C)C)c(=O)c3c2s1 Show InChI InChI=1S/C17H20N4O2S/c1-4-5-8-23-15(18)16-20-12-7-6-11-13(14(12)24-16)17(22)21(9-19-11)10(2)3/h6-7,9-10,18H,4-5,8H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Université de Nantes Curated by ChEMBL					Assay Description Inhibition of GSK3alpha/beta (unknown origin)				Eur J Med Chem 43: 1469-77 (2008) Article DOI: 10.1016/j.ejmech.2007.09.020 BindingDB Entry DOI: 10.7270/Q24M9495
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50247417 (8-Isopropyl-9-oxo-8,9-dihydro-thiazolo[5,4-f]quina...) Show SMILES CCCCOC(=N)c1nc2ccc3ncn(C(C)C)c(=O)c3c2s1 Show InChI InChI=1S/C17H20N4O2S/c1-4-5-8-23-15(18)16-20-12-7-6-11-13(14(12)24-16)17(22)21(9-19-11)10(2)3/h6-7,9-10,18H,4-5,8H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Nantes Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclinB (unknown origin)				Eur J Med Chem 43: 1469-77 (2008) Article DOI: 10.1016/j.ejmech.2007.09.020 BindingDB Entry DOI: 10.7270/Q24M9495
					More data for this Ligand-Target Pair