BDBM50247427 CHEMBL4064659

SMILES: Oc1ccc2ccccc2c1\C=N\NC(=O)c1ccc(c(Cl)c1)[N+]([O-])=O

InChI Key: InChIKey=DQNQYNSKEXTILY-KEBDBYFISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247427   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribonucleoside-diphosphate reductase large subunit (Homo sapiens (Human))	BDBM50247427 (CHEMBL4064659) Show SMILES Oc1ccc2ccccc2c1\C=N\NC(=O)c1ccc(c(Cl)c1)[N+]([O-])=O Show InChI InChI=1S/C18H12ClN3O4/c19-15-9-12(5-7-16(15)22(25)26)18(24)21-20-10-14-13-4-2-1-3-11(13)6-8-17(14)23/h1-10,23H,(H,21,24)/b20-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by ChEMBL					Assay Description Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...				J Med Chem 61: 666-680 (2018) BindingDB Entry DOI: 10.7270/Q2W098CB
					More data for this Ligand-Target Pair