BDBM50247433 CHEMBL4059739
SMILES: COc1cc(Br)ccc1C(=O)N\N=C\c1c(O)ccc2ccccc12
InChI Key: InChIKey=GPBCLOCWXXEQLK-SRZZPIQSSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ribonucleoside-diphosphate reductase large subunit (Homo sapiens (Human)) | BDBM50247433 (CHEMBL4059739) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Case Western Reserve University Curated by ChEMBL | Assay Description Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou... | J Med Chem 61: 666-680 (2018) BindingDB Entry DOI: 10.7270/Q2W098CB | |||||||||||
More data for this Ligand-Target Pair |