BDBM50247434 CHEMBL1958235

SMILES: Cc1ccc(cc1)S(=O)(=O)N\N=C\c1c(O)ccc2ccccc12

InChI Key: InChIKey=RGNFUPWYQNYCNG-XDHOZWIPSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50247434   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribonucleoside-diphosphate reductase large subunit (Homo sapiens (Human))	BDBM50247434 (CHEMBL1958235) Show SMILES Cc1ccc(cc1)S(=O)(=O)N\N=C\c1c(O)ccc2ccccc12 Show InChI InChI=1S/C18H16N2O3S/c1-13-6-9-15(10-7-13)24(22,23)20-19-12-17-16-5-3-2-4-14(16)8-11-18(17)21/h2-12,20-21H,1H3/b19-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by ChEMBL					Assay Description Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...				J Med Chem 61: 666-680 (2018) BindingDB Entry DOI: 10.7270/Q2W098CB
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50247434 (CHEMBL1958235) Show SMILES Cc1ccc(cc1)S(=O)(=O)N\N=C\c1c(O)ccc2ccccc12 Show InChI InChI=1S/C18H16N2O3S/c1-13-6-9-15(10-7-13)24(22,23)20-19-12-17-16-5-3-2-4-14(16)8-11-18(17)21/h2-12,20-21H,1H3/b19-12+	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Magna Grecia di Catanzaro Curated by ChEMBL					Assay Description Inhibition of ribonuclease H activity of HIV1 reverse transcriptase using as poly(dC)-[3H]poly(rG) as substrate				Eur J Med Chem 50: 216-29 (2012) Article DOI: 10.1016/j.ejmech.2012.01.056 BindingDB Entry DOI: 10.7270/Q2G163Q7
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50247434 (CHEMBL1958235) Show SMILES Cc1ccc(cc1)S(=O)(=O)N\N=C\c1c(O)ccc2ccccc12 Show InChI InChI=1S/C18H16N2O3S/c1-13-6-9-15(10-7-13)24(22,23)20-19-12-17-16-5-3-2-4-14(16)8-11-18(17)21/h2-12,20-21H,1H3/b19-12+	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Magna Grecia di Catanzaro Curated by ChEMBL					Assay Description Inhibition of RNA-dependent DNA polymerase activity of Human immunodeficiency virus 1 reverse transcriptase				Eur J Med Chem 50: 216-29 (2012) Article DOI: 10.1016/j.ejmech.2012.01.056 BindingDB Entry DOI: 10.7270/Q2G163Q7
					More data for this Ligand-Target Pair