BDBM50247534 CHEMBL4081035
SMILES: Cc1nc(-c2cnn(C)c2-c2ccc(cn2)C(F)(F)F)c2c(N)ncnn12
InChI Key: InChIKey=NNYRPUKGCYQBTE-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human)) | BDBM50247534 (CHEMBL4081035) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of full length human N-terminal FLAG-tagged PDE2A3 expressed in sf21 cells using [3H]cGMP as substrate after 30 mins by SPA | J Med Chem 61: 1001-1018 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZZ4 | |||||||||||
More data for this Ligand-Target Pair |