BDBM50247562 CHEMBL4064437

SMILES: Cc1ccc2cccc(NCc3ccc(cc3)C(=O)NO)c2n1

InChI Key: InChIKey=INODTFDZEFDMBH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247562   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50247562 (CHEMBL4064437) Show SMILES Cc1ccc2cccc(NCc3ccc(cc3)C(=O)NO)c2n1 Show InChI InChI=1S/C18H17N3O2/c1-12-5-8-14-3-2-4-16(17(14)20-12)19-11-13-6-9-15(10-7-13)18(22)21-23/h2-10,19,23H,11H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...				J Med Chem 61: 905-917 (2018) BindingDB Entry DOI: 10.7270/Q2Q81GGB
					More data for this Ligand-Target Pair