BDBM50247568 CHEMBL4060433

SMILES: ONC(=O)c1ccc(cc1)C(=O)Nc1cccc2ncccc12

InChI Key: InChIKey=QJVVGGNMEWIDAP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50247568 (CHEMBL4060433) Show SMILES ONC(=O)c1ccc(cc1)C(=O)Nc1cccc2ncccc12 Show InChI InChI=1S/C17H13N3O3/c21-16(11-6-8-12(9-7-11)17(22)20-23)19-15-5-1-4-14-13(15)3-2-10-18-14/h1-10,23H,(H,19,21)(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	525	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...				J Med Chem 61: 905-917 (2018) BindingDB Entry DOI: 10.7270/Q2Q81GGB
					More data for this Ligand-Target Pair