BDBM50247569 CHEMBL4069121

SMILES: ONC(=O)\C=C\c1ccc(CNc2cccc3ncccc23)cc1

InChI Key: InChIKey=NYMPIVCAZDUYFS-ZHACJKMWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247569   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50247569 (CHEMBL4069121) Show SMILES ONC(=O)\C=C\c1ccc(CNc2cccc3ncccc23)cc1 Show InChI InChI=1S/C19H17N3O2/c23-19(22-24)11-10-14-6-8-15(9-7-14)13-21-18-5-1-4-17-16(18)3-2-12-20-17/h1-12,21,24H,13H2,(H,22,23)/b11-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...				J Med Chem 61: 905-917 (2018) BindingDB Entry DOI: 10.7270/Q2Q81GGB
					More data for this Ligand-Target Pair