BDBM50247671 2-[1'-Phenyl-3'-(3-chlorophenyl)-2'-propenylidene]hydrazine-3-methyl-4(3H)-quinazolinone::CHEMBL453369

SMILES: Cn1c(N=NC(=CCc2cccc(Cl)c2)c2ccccc2)nc2ccccc2c1=O

InChI Key: InChIKey=KOMLFNUEJOALBN-UHFFFAOYSA-N

Data: 2 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50247671   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50247671 (2-[1'-Phenyl-3'-(3-chlorophenyl)-2'-propenylidene]...) Show SMILES Cn1c(N=NC(=CCc2cccc(Cl)c2)c2ccccc2)nc2ccccc2c1=O |w:6.6,3.2| Show InChI InChI=1S/C24H19ClN4O/c1-29-23(30)20-12-5-6-13-22(20)26-24(29)28-27-21(18-9-3-2-4-10-18)15-14-17-8-7-11-19(25)16-17/h2-13,15-16H,14H2,1H3	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Inhibition of MAO-B in rat liver homogenate after 60 mins by Lineweaver-Burk plot				Bioorg Med Chem 17: 675-89 (2009) Article DOI: 10.1016/j.bmc.2008.11.068 BindingDB Entry DOI: 10.7270/Q2BG2NWT
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50247671 (2-[1'-Phenyl-3'-(3-chlorophenyl)-2'-propenylidene]...) Show SMILES Cn1c(N=NC(=CCc2cccc(Cl)c2)c2ccccc2)nc2ccccc2c1=O |w:6.6,3.2| Show InChI InChI=1S/C24H19ClN4O/c1-29-23(30)20-12-5-6-13-22(20)26-24(29)28-27-21(18-9-3-2-4-10-18)15-14-17-8-7-11-19(25)16-17/h2-13,15-16H,14H2,1H3	PDB MMDB B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver homogenate after 60 mins by Lineweaver-Burk plot				Bioorg Med Chem 17: 675-89 (2009) Article DOI: 10.1016/j.bmc.2008.11.068 BindingDB Entry DOI: 10.7270/Q2BG2NWT
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50247671 (2-[1'-Phenyl-3'-(3-chlorophenyl)-2'-propenylidene]...) Show SMILES Cn1c(N=NC(=CCc2cccc(Cl)c2)c2ccccc2)nc2ccccc2c1=O |w:6.6,3.2| Show InChI InChI=1S/C24H19ClN4O/c1-29-23(30)20-12-5-6-13-22(20)26-24(29)28-27-21(18-9-3-2-4-10-18)15-14-17-8-7-11-19(25)16-17/h2-13,15-16H,14H2,1H3	PDB MMDB B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.68E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver homogenate after 60 mins by residual activity plot				Bioorg Med Chem 17: 675-89 (2009) Article DOI: 10.1016/j.bmc.2008.11.068 BindingDB Entry DOI: 10.7270/Q2BG2NWT
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50247671 (2-[1'-Phenyl-3'-(3-chlorophenyl)-2'-propenylidene]...) Show SMILES Cn1c(N=NC(=CCc2cccc(Cl)c2)c2ccccc2)nc2ccccc2c1=O |w:6.6,3.2| Show InChI InChI=1S/C24H19ClN4O/c1-29-23(30)20-12-5-6-13-22(20)26-24(29)28-27-21(18-9-3-2-4-10-18)15-14-17-8-7-11-19(25)16-17/h2-13,15-16H,14H2,1H3	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Inhibition of MAO-B in rat liver homogenate after 60 mins by residual activity plot				Bioorg Med Chem 17: 675-89 (2009) Article DOI: 10.1016/j.bmc.2008.11.068 BindingDB Entry DOI: 10.7270/Q2BG2NWT
					More data for this Ligand-Target Pair