BDBM50247911 2-(4-Pyridyl)-isothiazol-3(2H)-one::CHEMBL499919

SMILES: O=c1ccsn1-c1ccncc1

InChI Key: InChIKey=SKMYNTBICARDSP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50247911   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50247911 (2-(4-Pyridyl)-isothiazol-3(2H)-one | CHEMBL499919) Show SMILES O=c1ccsn1-c1ccncc1 Show InChI InChI=1S/C8H6N2OS/c11-8-3-6-12-10(8)7-1-4-9-5-2-7/h1-6H	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT p300 expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase PCAF (Homo sapiens (Human))	BDBM50247911 (2-(4-Pyridyl)-isothiazol-3(2H)-one | CHEMBL499919) Show SMILES O=c1ccsn1-c1ccncc1 Show InChI InChI=1S/C8H6N2OS/c11-8-3-6-12-10(8)7-1-4-9-5-2-7/h1-6H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair