BDBM50247928 CHEMBL489902::N-(2-aminophenyl)-3-(2-phenethyl-1-(pyridin-2-ylmethyl)-1H-benzo[d]imidazol-5-yl)acrylamide

SMILES: Nc1ccccc1NC(=O)\C=C\c1ccc2n(Cc3ccccn3)c(CCc3ccccc3)nc2c1

InChI Key: InChIKey=KQTPKKGWZCMLER-OBGWFSINSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50247928 (CHEMBL489902 | N-(2-aminophenyl)-3-(2-phenethyl-1-...) Show SMILES Nc1ccccc1NC(=O)\C=C\c1ccc2n(Cc3ccccn3)c(CCc3ccccc3)nc2c1 Show InChI InChI=1S/C30H27N5O/c31-25-11-4-5-12-26(25)34-30(36)18-15-23-13-16-28-27(20-23)33-29(17-14-22-8-2-1-3-9-22)35(28)21-24-10-6-7-19-32-24/h1-13,15-16,18-20H,14,17,21,31H2,(H,34,36)/b18-15+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
S *BIO Pte Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC1 by fluorimetric assay				Bioorg Med Chem Lett 19: 1403-8 (2009) Article DOI: 10.1016/j.bmcl.2009.01.041 BindingDB Entry DOI: 10.7270/Q2FT8KX3
					More data for this Ligand-Target Pair