BDBM50248098 CHEMBL462148::N-((4-(azetidin-1-yl)-1-(propylsulfonyl)piperidin-4-yl)methyl)-2,4-dichlorobenzamide

SMILES: CCCS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(CC1)N1CCC1

InChI Key: InChIKey=WITNMAGOLNNLJI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248098   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM50248098 (CHEMBL462148 | N-((4-(azetidin-1-yl)-1-(propylsulf...) Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(CC1)N1CCC1 Show InChI InChI=1S/C19H27Cl2N3O3S/c1-2-12-28(26,27)24-10-6-19(7-11-24,23-8-3-9-23)14-22-18(25)16-5-4-15(20)13-17(16)21/h4-5,13H,2-3,6-12,14H2,1H3,(H,22,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of Glyt1				Bioorg Med Chem Lett 19: 1492-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.015 BindingDB Entry DOI: 10.7270/Q2B27V5N
					More data for this Ligand-Target Pair