null

SMILES: CN(CCC#N)C(=O)c1cccc(Nc2nsnc2N[C@@H](c2ccc(C)o2)C(C)(C)C)c1O

InChI Key: InChIKey=LUNAFTMLJLEOEQ-IBGZPJMESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248113   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50248113 ((R)-N-(2-cyanoethyl)-3-(4-(2,2-dimethyl-1-(5-methy...) Show SMILES CN(CCC#N)C(=O)c1cccc(Nc2nsnc2N[C@@H](c2ccc(C)o2)C(C)(C)C)c1O |r| Show InChI InChI=1S/C23H28N6O3S/c1-14-10-11-17(32-14)19(23(2,3)4)26-21-20(27-33-28-21)25-16-9-6-8-15(18(16)30)22(31)29(5)13-7-12-24/h6,8-11,19,30H,7,13H2,1-5H3,(H,25,27)(H,26,28)/t19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of IL8 from CXCR1 receptor (unknown origin)				Bioorg Med Chem Lett 19: 1434-7 (2009) Article DOI: 10.1016/j.bmcl.2009.01.027 BindingDB Entry DOI: 10.7270/Q2833RW1
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50248113 ((R)-N-(2-cyanoethyl)-3-(4-(2,2-dimethyl-1-(5-methy...) Show SMILES CN(CCC#N)C(=O)c1cccc(Nc2nsnc2N[C@@H](c2ccc(C)o2)C(C)(C)C)c1O |r| Show InChI InChI=1S/C23H28N6O3S/c1-14-10-11-17(32-14)19(23(2,3)4)26-21-20(27-33-28-21)25-16-9-6-8-15(18(16)30)22(31)29(5)13-7-12-24/h6,8-11,19,30H,7,13H2,1-5H3,(H,25,27)(H,26,28)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	114	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of IL8 from CXCR2 receptor (unknown origin)				Bioorg Med Chem Lett 19: 1434-7 (2009) Article DOI: 10.1016/j.bmcl.2009.01.027 BindingDB Entry DOI: 10.7270/Q2833RW1
					More data for this Ligand-Target Pair