null

SMILES: CN(CCC#N)C(=O)c1cccc(Nc2nsnc2N[C@@H](c2ccco2)C(C)(C)C)c1O

InChI Key: InChIKey=SCSNKXZAGMCAGA-SFHVURJKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50248115 ((R)-N-(2-cyanoethyl)-3-(4-(1-(furan-2-yl)-2,2-dime...) Show SMILES CN(CCC#N)C(=O)c1cccc(Nc2nsnc2N[C@@H](c2ccco2)C(C)(C)C)c1O |r| Show InChI InChI=1S/C22H26N6O3S/c1-22(2,3)18(16-10-6-13-31-16)25-20-19(26-32-27-20)24-15-9-5-8-14(17(15)29)21(30)28(4)12-7-11-23/h5-6,8-10,13,18,29H,7,12H2,1-4H3,(H,24,26)(H,25,27)/t18-/m0/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of IL8 from CXCR1 receptor (unknown origin)				Bioorg Med Chem Lett 19: 1434-7 (2009) Article DOI: 10.1016/j.bmcl.2009.01.027 BindingDB Entry DOI: 10.7270/Q2833RW1
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50248115 ((R)-N-(2-cyanoethyl)-3-(4-(1-(furan-2-yl)-2,2-dime...) Show SMILES CN(CCC#N)C(=O)c1cccc(Nc2nsnc2N[C@@H](c2ccco2)C(C)(C)C)c1O |r| Show InChI InChI=1S/C22H26N6O3S/c1-22(2,3)18(16-10-6-13-31-16)25-20-19(26-32-27-20)24-15-9-5-8-14(17(15)29)21(30)28(4)12-7-11-23/h5-6,8-10,13,18,29H,7,12H2,1-4H3,(H,24,26)(H,25,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of IL8 from CXCR2 receptor (unknown origin)				Bioorg Med Chem Lett 19: 1434-7 (2009) Article DOI: 10.1016/j.bmcl.2009.01.027 BindingDB Entry DOI: 10.7270/Q2833RW1
					More data for this Ligand-Target Pair