BDBM50248218 1-(4-Fluorophenylsulfonamido)-3-morpholinopropan-2-yl dihydrogen phosphate::CHEMBL473752::HEA derivative, 7b

SMILES: OP(O)(=O)OC(CNS(=O)(=O)c1ccc(F)cc1)CN1CCOCC1

InChI Key: InChIKey=PQONZGNIVZDUAK-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248218   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MurC (Escherichia coli)	BDBM50248218 (1-(4-Fluorophenylsulfonamido)-3-morpholinopropan-2...) Show SMILES OP(O)(=O)OC(CNS(=O)(=O)c1ccc(F)cc1)CN1CCOCC1 Show InChI InChI=1S/C13H20FN2O7PS/c14-11-1-3-13(4-2-11)25(20,21)15-9-12(23-24(17,18)19)10-16-5-7-22-8-6-16/h1-4,12,15H,5-10H2,(H2,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90E+5	n/a	n/a	n/a	n/a	8.0	37
University of Ljubljana					Assay Description Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...				Bioorg Chem 37: 217-22 (2009) Article DOI: 10.1016/j.bioorg.2009.09.001 BindingDB Entry DOI: 10.7270/Q2D21W5D
					More data for this Ligand-Target Pair
Vancomycin/teicoplanin A-type resistance protein vanA (Enterococcus faecium)	BDBM50248218 (1-(4-Fluorophenylsulfonamido)-3-morpholinopropan-2...) Show SMILES OP(O)(=O)OC(CNS(=O)(=O)c1ccc(F)cc1)CN1CCOCC1 Show InChI InChI=1S/C13H20FN2O7PS/c14-11-1-3-13(4-2-11)25(20,21)15-9-12(23-24(17,18)19)10-16-5-7-22-8-6-16/h1-4,12,15H,5-10H2,(H2,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Enterococcus faecium VanA by pyruvate kinase/lactate dehydrogenase coupled assay				Bioorg Med Chem Lett 19: 1376-9 (2009) Article DOI: 10.1016/j.bmcl.2009.01.034 BindingDB Entry DOI: 10.7270/Q2HM58B5
					More data for this Ligand-Target Pair
MurF (Escherichia coli)	BDBM50248218 (1-(4-Fluorophenylsulfonamido)-3-morpholinopropan-2...) Show SMILES OP(O)(=O)OC(CNS(=O)(=O)c1ccc(F)cc1)CN1CCOCC1 Show InChI InChI=1S/C13H20FN2O7PS/c14-11-1-3-13(4-2-11)25(20,21)15-9-12(23-24(17,18)19)10-16-5-7-22-8-6-16/h1-4,12,15H,5-10H2,(H2,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+5	n/a	n/a	n/a	n/a	8.0	37
University of Ljubljana					Assay Description Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...				Bioorg Chem 37: 217-22 (2009) Article DOI: 10.1016/j.bioorg.2009.09.001 BindingDB Entry DOI: 10.7270/Q2D21W5D
					More data for this Ligand-Target Pair
MurE (Staphylococcus aureus)	BDBM50248218 (1-(4-Fluorophenylsulfonamido)-3-morpholinopropan-2...) Show SMILES OP(O)(=O)OC(CNS(=O)(=O)c1ccc(F)cc1)CN1CCOCC1 Show InChI InChI=1S/C13H20FN2O7PS/c14-11-1-3-13(4-2-11)25(20,21)15-9-12(23-24(17,18)19)10-16-5-7-22-8-6-16/h1-4,12,15H,5-10H2,(H2,17,18,19)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	8.0	37
University of Ljubljana					Assay Description Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...				Bioorg Chem 37: 217-22 (2009) Article DOI: 10.1016/j.bioorg.2009.09.001 BindingDB Entry DOI: 10.7270/Q2D21W5D
					More data for this Ligand-Target Pair