BDBM50248257 (E)-N-hydroxy-3-(1-(3-hydroxypropyl)-1H-benzo[d]imidazol-5-yl)acrylamide::CHEMBL507008::US10201527, Compound 47::US10736881, Compound 47

SMILES: OCCCn1cnc2cc(\C=C\C(=O)NO)ccc12

InChI Key: InChIKey=OUFDENCCUPKHBQ-HWKANZROSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50248257   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50248257 ((E)-N-hydroxy-3-(1-(3-hydroxypropyl)-1H-benzo[d]im...) Show SMILES OCCCn1cnc2cc(\C=C\C(=O)NO)ccc12 Show InChI InChI=1S/C13H15N3O3/c17-7-1-6-16-9-14-11-8-10(2-4-12(11)16)3-5-13(18)15-19/h2-5,8-9,17,19H,1,6-7H2,(H,15,18)/b5-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
S *BIO Pte Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC1 by fluorimetric assay				Bioorg Med Chem Lett 19: 1403-8 (2009) Article DOI: 10.1016/j.bmcl.2009.01.041 BindingDB Entry DOI: 10.7270/Q2FT8KX3
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50248257 ((E)-N-hydroxy-3-(1-(3-hydroxypropyl)-1H-benzo[d]im...) Show SMILES OCCCn1cnc2cc(\C=C\C(=O)NO)ccc12 Show InChI InChI=1S/C13H15N3O3/c17-7-1-6-16-9-14-11-8-10(2-4-12(11)16)3-5-13(18)15-19/h2-5,8-9,17,19H,1,6-7H2,(H,15,18)/b5-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
MEI Pharma, Inc. US Patent					Assay Description The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...				US Patent US10736881 (2020)
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50248257 ((E)-N-hydroxy-3-(1-(3-hydroxypropyl)-1H-benzo[d]im...) Show SMILES OCCCn1cnc2cc(\C=C\C(=O)NO)ccc12 Show InChI InChI=1S/C13H15N3O3/c17-7-1-6-16-9-14-11-8-10(2-4-12(11)16)3-5-13(18)15-19/h2-5,8-9,17,19H,1,6-7H2,(H,15,18)/b5-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
MEI PHARMA, INC. US Patent					Assay Description The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...				US Patent US10201527 (2019) BindingDB Entry DOI: 10.7270/Q2PK0J7F
					More data for this Ligand-Target Pair