BDBM50248545 (S)-3-(2-(1-(benzo[d][1,3]dioxol-5-yl)-2,2,2-trifluoroethylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide::CHEMBL518857
SMILES: CN(C)C(=O)c1cccc(Nc2c(N[C@@H](c3ccc4OCOc4c3)C(F)(F)F)c(=O)c2=O)c1O
InChI Key: InChIKey=YVZGSKYWJOEQBN-FQEVSTJZSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50248545 ((S)-3-(2-(1-(benzo[d][1,3]dioxol-5-yl)-2,2,2-trifl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Binding affinity to CXCR2 (unknown origin) | Bioorg Med Chem Lett 19: 1431-3 (2009) Article DOI: 10.1016/j.bmcl.2009.01.033 BindingDB Entry DOI: 10.7270/Q2CV4HMF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50248545 ((S)-3-(2-(1-(benzo[d][1,3]dioxol-5-yl)-2,2,2-trifl...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Binding affinity to CXCR1 (unknown origin) | Bioorg Med Chem Lett 19: 1431-3 (2009) Article DOI: 10.1016/j.bmcl.2009.01.033 BindingDB Entry DOI: 10.7270/Q2CV4HMF | |||||||||||
More data for this Ligand-Target Pair |