BDBM50248574 CHEMBL464927::N-hydroxy-2-(1-methyl-2-phenethyl-1H-benzo[d]imidazol-5-yl)cyclopropanecarboxamide

SMILES: Cn1c(CCc2ccccc2)nc2cc(ccc12)C1CC1C(=O)NO

InChI Key: InChIKey=CJEAJAOQWHRYLM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50248574 (CHEMBL464927 | N-hydroxy-2-(1-methyl-2-phenethyl-1...) Show SMILES Cn1c(CCc2ccccc2)nc2cc(ccc12)C1CC1C(=O)NO Show InChI InChI=1S/C20H21N3O2/c1-23-18-9-8-14(15-12-16(15)20(24)22-25)11-17(18)21-19(23)10-7-13-5-3-2-4-6-13/h2-6,8-9,11,15-16,25H,7,10,12H2,1H3,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
S *BIO Pte Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC1 by fluorimetric assay				Bioorg Med Chem Lett 19: 1403-8 (2009) Article DOI: 10.1016/j.bmcl.2009.01.041 BindingDB Entry DOI: 10.7270/Q2FT8KX3
					More data for this Ligand-Target Pair