BDBM50248589 2-hydroxy-N,N-dimethyl-3-(4-(2,2,2-trifluoro-1-phenylethylamino)-1,2,5-thiadiazol-3-ylamino)benzamide::CHEMBL517430

SMILES: CN(C)C(=O)c1cccc(Nc2nsnc2NC(c2ccccc2)C(F)(F)F)c1O

InChI Key: InChIKey=NCGKJISZBYAIJV-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248589   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50248589 (2-hydroxy-N,N-dimethyl-3-(4-(2,2,2-trifluoro-1-phe...) Show SMILES CN(C)C(=O)c1cccc(Nc2nsnc2NC(c2ccccc2)C(F)(F)F)c1O Show InChI InChI=1S/C19H18F3N5O2S/c1-27(2)18(29)12-9-6-10-13(14(12)28)23-16-17(26-30-25-16)24-15(19(20,21)22)11-7-4-3-5-8-11/h3-10,15,28H,1-2H3,(H,23,25)(H,24,26)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of IL8 from CXCR1 receptor (unknown origin)				Bioorg Med Chem Lett 19: 1434-7 (2009) Article DOI: 10.1016/j.bmcl.2009.01.027 BindingDB Entry DOI: 10.7270/Q2833RW1
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50248589 (2-hydroxy-N,N-dimethyl-3-(4-(2,2,2-trifluoro-1-phe...) Show SMILES CN(C)C(=O)c1cccc(Nc2nsnc2NC(c2ccccc2)C(F)(F)F)c1O Show InChI InChI=1S/C19H18F3N5O2S/c1-27(2)18(29)12-9-6-10-13(14(12)28)23-16-17(26-30-25-16)24-15(19(20,21)22)11-7-4-3-5-8-11/h3-10,15,28H,1-2H3,(H,23,25)(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of IL8 from CXCR2 receptor (unknown origin)				Bioorg Med Chem Lett 19: 1434-7 (2009) Article DOI: 10.1016/j.bmcl.2009.01.027 BindingDB Entry DOI: 10.7270/Q2833RW1
					More data for this Ligand-Target Pair