Found 3 hits for monomerid = 50248644 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Glycine transporter 2
(Homo sapiens (Human)) | BDBM50248644
(2-methyl-N-((1-(propylsulfonyl)-4-(pyridin-2-yl)pi...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2C)(CC1)c1ccccn1 Show InChI InChI=1S/C22H29N3O3S/c1-3-16-29(27,28)25-14-11-22(12-15-25,20-10-6-7-13-23-20)17-24-21(26)19-9-5-4-8-18(19)2/h4-10,13H,3,11-12,14-17H2,1-2H3,(H,24,26) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description Inhibition of glycine transporter 2 |
Bioorg Med Chem Lett 19: 1488-91 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.115 BindingDB Entry DOI: 10.7270/Q2V124P3 |
More data for this Ligand-Target Pair | |
Sodium- and chloride-dependent taurine transporter
(Homo sapiens (Human)) | BDBM50248644
(2-methyl-N-((1-(propylsulfonyl)-4-(pyridin-2-yl)pi...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2C)(CC1)c1ccccn1 Show InChI InChI=1S/C22H29N3O3S/c1-3-16-29(27,28)25-14-11-22(12-15-25,20-10-6-7-13-23-20)17-24-21(26)19-9-5-4-8-18(19)2/h4-10,13H,3,11-12,14-17H2,1-2H3,(H,24,26) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description Inhibition of taurine transporter |
Bioorg Med Chem Lett 19: 1488-91 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.115 BindingDB Entry DOI: 10.7270/Q2V124P3 |
More data for this Ligand-Target Pair | |
Glycine transporter 1
(Homo sapiens (Human)) | BDBM50248644
(2-methyl-N-((1-(propylsulfonyl)-4-(pyridin-2-yl)pi...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2C)(CC1)c1ccccn1 Show InChI InChI=1S/C22H29N3O3S/c1-3-16-29(27,28)25-14-11-22(12-15-25,20-10-6-7-13-23-20)17-24-21(26)19-9-5-4-8-18(19)2/h4-10,13H,3,11-12,14-17H2,1-2H3,(H,24,26) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description Inhibition of human glycine transporter 1 |
Bioorg Med Chem Lett 19: 1488-91 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.115 BindingDB Entry DOI: 10.7270/Q2V124P3 |
More data for this Ligand-Target Pair | |