Found 3 hits for monomerid = 50248653 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Glycine transporter 2
(Homo sapiens (Human)) | BDBM50248653
(2-chloro-N-((4-(6-methoxypyridin-2-yl)-1-(propylsu...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2Cl)(CC1)c1cccc(OC)n1 Show InChI InChI=1S/C22H28ClN3O4S/c1-3-15-31(28,29)26-13-11-22(12-14-26,19-9-6-10-20(25-19)30-2)16-24-21(27)17-7-4-5-8-18(17)23/h4-10H,3,11-16H2,1-2H3,(H,24,27) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description Inhibition of glycine transporter 2 |
Bioorg Med Chem Lett 19: 1488-91 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.115 BindingDB Entry DOI: 10.7270/Q2V124P3 |
More data for this Ligand-Target Pair | |
Sodium- and chloride-dependent taurine transporter
(Homo sapiens (Human)) | BDBM50248653
(2-chloro-N-((4-(6-methoxypyridin-2-yl)-1-(propylsu...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2Cl)(CC1)c1cccc(OC)n1 Show InChI InChI=1S/C22H28ClN3O4S/c1-3-15-31(28,29)26-13-11-22(12-14-26,19-9-6-10-20(25-19)30-2)16-24-21(27)17-7-4-5-8-18(17)23/h4-10H,3,11-16H2,1-2H3,(H,24,27) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description Inhibition of taurine transporter |
Bioorg Med Chem Lett 19: 1488-91 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.115 BindingDB Entry DOI: 10.7270/Q2V124P3 |
More data for this Ligand-Target Pair | |
Glycine transporter 1
(Homo sapiens (Human)) | BDBM50248653
(2-chloro-N-((4-(6-methoxypyridin-2-yl)-1-(propylsu...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2Cl)(CC1)c1cccc(OC)n1 Show InChI InChI=1S/C22H28ClN3O4S/c1-3-15-31(28,29)26-13-11-22(12-14-26,19-9-6-10-20(25-19)30-2)16-24-21(27)17-7-4-5-8-18(17)23/h4-10H,3,11-16H2,1-2H3,(H,24,27) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description Inhibition of human glycine transporter 1 |
Bioorg Med Chem Lett 19: 1488-91 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.115 BindingDB Entry DOI: 10.7270/Q2V124P3 |
More data for this Ligand-Target Pair | |