BDBM50248861 CHEMBL4078347

SMILES: O=C1NC(=S)S\C1=C/c1csc(n1)-c1cccnc1

InChI Key: InChIKey=SWTGHOLVKWWDRK-WTKPLQERSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248861   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50248861 (CHEMBL4078347) Show SMILES O=C1NC(=S)S\C1=C/c1csc(n1)-c1cccnc1 Show InChI InChI=1S/C12H7N3OS3/c16-10-9(19-12(17)15-10)4-8-6-18-11(14-8)7-2-1-3-13-5-7/h1-6H,(H,15,16,17)/b9-4-	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assay				Bioorg Med Chem 25: 2657-2665 (2017) Article DOI: 10.1016/j.bmc.2017.02.056 BindingDB Entry DOI: 10.7270/Q2CV4M5V
					More data for this Ligand-Target Pair