BDBM50248864 CHEMBL4090574

SMILES: O=C1NC(=S)S\C1=C/c1csc(n1)-c1ccsc1

InChI Key: InChIKey=OEZABFQGMCLDFW-BAQGIRSFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248864   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50248864 (CHEMBL4090574) Show SMILES O=C1NC(=S)S\C1=C/c1csc(n1)-c1ccsc1 Show InChI InChI=1S/C11H6N2OS4/c14-9-8(18-11(15)13-9)3-7-5-17-10(12-7)6-1-2-16-4-6/h1-5H,(H,13,14,15)/b8-3-	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assay				Bioorg Med Chem 25: 2657-2665 (2017) Article DOI: 10.1016/j.bmc.2017.02.056 BindingDB Entry DOI: 10.7270/Q2CV4M5V
					More data for this Ligand-Target Pair