BDBM50248902 CHEMBL4087384

SMILES: FC(F)(F)c1cccc(c1)-c1nc(\C=C2/SC(=S)NC2=O)cs1

InChI Key: InChIKey=SNODLRZRENSASP-YHYXMXQVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248902   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50248902 (CHEMBL4087384) Show SMILES FC(F)(F)c1cccc(c1)-c1nc(\C=C2/SC(=S)NC2=O)cs1 Show InChI InChI=1S/C14H7F3N2OS3/c15-14(16,17)8-3-1-2-7(4-8)12-18-9(6-22-12)5-10-11(20)19-13(21)23-10/h1-6H,(H,19,20,21)/b10-5-	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assay				Bioorg Med Chem 25: 2657-2665 (2017) Article DOI: 10.1016/j.bmc.2017.02.056 BindingDB Entry DOI: 10.7270/Q2CV4M5V
					More data for this Ligand-Target Pair