BDBM50248990 14beta-(4-Methylcinnamoyloxy)-N-cyclopropylmethyl-7,8-dihydronormorphinone::CHEMBL474641

SMILES: Cc1ccc(\C=C\C(=O)O[C@]23CCC(=O)[C@@H]4Oc5c6c(C[C@H]2N(CC2CC2)CC[C@@]346)ccc5O)cc1

InChI Key: InChIKey=NMTMBZUBWPVSPH-SHEAVXILSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (GUINEA PIG)	BDBM50248990 (14beta-(4-Methylcinnamoyloxy)-N-cyclopropylmethyl-...) Show SMILES Cc1ccc(\C=C\C(=O)O[C@]23CCC(=O)[C@@H]4Oc5c6c(C[C@H]2N(CC2CC2)CC[C@@]346)ccc5O)cc1 |r| Show InChI InChI=1S/C30H31NO5/c1-18-2-4-19(5-3-18)8-11-25(34)36-30-13-12-23(33)28-29(30)14-15-31(17-20-6-7-20)24(30)16-21-9-10-22(32)27(35-28)26(21)29/h2-5,8-11,20,24,28,32H,6-7,12-17H2,1H3/b11-8+/t24-,28+,29+,30-/m1/s1	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in Hartely guinea pig brain membrane				J Med Chem 52: 1553-7 (2009) Article DOI: 10.1021/jm8012272 BindingDB Entry DOI: 10.7270/Q2G44R6N
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50248990 (14beta-(4-Methylcinnamoyloxy)-N-cyclopropylmethyl-...) Show SMILES Cc1ccc(\C=C\C(=O)O[C@]23CCC(=O)[C@@H]4Oc5c6c(C[C@H]2N(CC2CC2)CC[C@@]346)ccc5O)cc1 |r| Show InChI InChI=1S/C30H31NO5/c1-18-2-4-19(5-3-18)8-11-25(34)36-30-13-12-23(33)28-29(30)14-15-31(17-20-6-7-20)24(30)16-21-9-10-22(32)27(35-28)26(21)29/h2-5,8-11,20,24,28,32H,6-7,12-17H2,1H3/b11-8+/t24-,28+,29+,30-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Displacement of [3H]U69,593 from kappa opioid receptor in Hartely guinea pig brain membrane				J Med Chem 52: 1553-7 (2009) Article DOI: 10.1021/jm8012272 BindingDB Entry DOI: 10.7270/Q2G44R6N
					More data for this Ligand-Target Pair