null

SMILES: CC1(CC2c3ccccc3C1c1ccccc21)C(=O)Nc1ccc(cc1O)[N+]([O-])=O

InChI Key: InChIKey=RWELAKLWFPYJLK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249105   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50249105 (CHEMBL514185 | N-(2-hydroxy-4-nitrophenyl)-15-meth...) Show SMILES CC1(CC2c3ccccc3C1c1ccccc21)C(=O)Nc1ccc(cc1O)[N+]([O-])=O |TLB:0:1:4.9:11.16,8:9:2.1:11.16,12:11:4.9:2.1,THB:17:1:4.9:11.16,(21.57,-.39,;22.91,-1.16,;23.42,-1.93,;23.43,-4.12,;21.56,-4.64,;20.22,-5.41,;18.88,-4.64,;18.89,-3.09,;20.21,-2.32,;21.52,-3.24,;22.91,-2.58,;24.45,-3.47,;25.72,-2.73,;27,-3.46,;27,-4.95,;25.72,-5.69,;24.44,-4.95,;23.67,.18,;22.88,1.51,;25.21,.2,;25.97,1.54,;25.19,2.86,;25.94,4.2,;27.49,4.22,;28.27,2.89,;27.52,1.55,;28.3,.22,;28.23,5.57,;29.78,5.59,;27.45,6.9,)| Show InChI InChI=1S/C24H20N2O4/c1-24(23(28)25-20-11-10-14(26(29)30)12-21(20)27)13-19-15-6-2-4-8-17(15)22(24)18-9-5-3-7-16(18)19/h2-12,19,22,27H,13H2,1H3,(H,25,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Displacement of FITC-dexamethasone from human recombinant glucocorticoid receptor alpha by fluorescence polarization assay				Bioorg Med Chem Lett 19: 2139-43 (2009) Article DOI: 10.1016/j.bmcl.2009.03.006 BindingDB Entry DOI: 10.7270/Q2XW4KRC
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50249105 (CHEMBL514185 | N-(2-hydroxy-4-nitrophenyl)-15-meth...) Show SMILES CC1(CC2c3ccccc3C1c1ccccc21)C(=O)Nc1ccc(cc1O)[N+]([O-])=O |TLB:0:1:4.9:11.16,8:9:2.1:11.16,12:11:4.9:2.1,THB:17:1:4.9:11.16,(21.57,-.39,;22.91,-1.16,;23.42,-1.93,;23.43,-4.12,;21.56,-4.64,;20.22,-5.41,;18.88,-4.64,;18.89,-3.09,;20.21,-2.32,;21.52,-3.24,;22.91,-2.58,;24.45,-3.47,;25.72,-2.73,;27,-3.46,;27,-4.95,;25.72,-5.69,;24.44,-4.95,;23.67,.18,;22.88,1.51,;25.21,.2,;25.97,1.54,;25.19,2.86,;25.94,4.2,;27.49,4.22,;28.27,2.89,;27.52,1.55,;28.3,.22,;28.23,5.57,;29.78,5.59,;27.45,6.9,)| Show InChI InChI=1S/C24H20N2O4/c1-24(23(28)25-20-11-10-14(26(29)30)12-21(20)27)13-19-15-6-2-4-8-17(15)22(24)18-9-5-3-7-16(18)19/h2-12,19,22,27H,13H2,1H3,(H,25,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transrepression activity at GR in PMA-stimulated human A549 cells assessed as inhibition of AP1 response element-induced luciferase reporter gene act...				Bioorg Med Chem Lett 19: 2139-43 (2009) Article DOI: 10.1016/j.bmcl.2009.03.006 BindingDB Entry DOI: 10.7270/Q2XW4KRC
					More data for this Ligand-Target Pair