null

SMILES: CC1(CC2c3ccccc3C1c1ccccc21)C(=O)Nc1ncc[nH]1

InChI Key: InChIKey=SPRNBEPBURHNIM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249191   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50249191 (CHEMBL474381 | N-(1H-imidazol-2-yl)-15-methyltetra...) Show SMILES CC1(CC2c3ccccc3C1c1ccccc21)C(=O)Nc1ncc[nH]1 |TLB:0:1:4.9:11.16,8:9:2.1:11.16,12:11:4.9:2.1,THB:17:1:4.9:11.16,(29.36,-32.07,;30.71,-32.85,;31.21,-33.62,;31.22,-35.81,;29.35,-36.33,;28.01,-37.1,;26.67,-36.33,;26.67,-34.78,;28,-34.01,;29.32,-34.93,;30.71,-34.27,;32.24,-35.16,;33.52,-34.42,;34.8,-35.16,;34.8,-36.64,;33.52,-37.38,;32.24,-36.64,;31.46,-31.51,;30.68,-30.18,;33.01,-31.49,;33.76,-30.14,;35.3,-29.96,;35.61,-28.45,;34.26,-27.69,;33.13,-28.74,)| Show InChI InChI=1S/C21H19N3O/c1-21(19(25)24-20-22-10-11-23-20)12-17-13-6-2-4-8-15(13)18(21)16-9-5-3-7-14(16)17/h2-11,17-18H,12H2,1H3,(H2,22,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	92.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Displacement of FITC-dexamethasone from human recombinant glucocorticoid receptor alpha by fluorescence polarization assay				Bioorg Med Chem Lett 19: 2139-43 (2009) Article DOI: 10.1016/j.bmcl.2009.03.006 BindingDB Entry DOI: 10.7270/Q2XW4KRC
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50249191 (CHEMBL474381 | N-(1H-imidazol-2-yl)-15-methyltetra...) Show SMILES CC1(CC2c3ccccc3C1c1ccccc21)C(=O)Nc1ncc[nH]1 |TLB:0:1:4.9:11.16,8:9:2.1:11.16,12:11:4.9:2.1,THB:17:1:4.9:11.16,(29.36,-32.07,;30.71,-32.85,;31.21,-33.62,;31.22,-35.81,;29.35,-36.33,;28.01,-37.1,;26.67,-36.33,;26.67,-34.78,;28,-34.01,;29.32,-34.93,;30.71,-34.27,;32.24,-35.16,;33.52,-34.42,;34.8,-35.16,;34.8,-36.64,;33.52,-37.38,;32.24,-36.64,;31.46,-31.51,;30.68,-30.18,;33.01,-31.49,;33.76,-30.14,;35.3,-29.96,;35.61,-28.45,;34.26,-27.69,;33.13,-28.74,)| Show InChI InChI=1S/C21H19N3O/c1-21(19(25)24-20-22-10-11-23-20)12-17-13-6-2-4-8-15(13)18(21)16-9-5-3-7-14(16)17/h2-11,17-18H,12H2,1H3,(H2,22,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transrepression activity at GR in PMA-stimulated human A549 cells assessed as inhibition of AP1 response element-induced luciferase reporter gene act...				Bioorg Med Chem Lett 19: 2139-43 (2009) Article DOI: 10.1016/j.bmcl.2009.03.006 BindingDB Entry DOI: 10.7270/Q2XW4KRC
					More data for this Ligand-Target Pair