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SMILES: COc1cc(Nc2nc(NC3CCCCC[C@H]3N)n3ccnc3c2C(N)=O)cc(OC)c1

InChI Key: InChIKey=XBSJTNRILPXSKD-TZHYSIJRSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249222   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM50249222
PNG
(5-((2R)-2-aminocycloheptylamino)-7-(3,5-dimethoxyp...)
Show SMILES COc1cc(Nc2nc(NC3CCCCC[C@H]3N)n3ccnc3c2C(N)=O)cc(OC)c1 |r|
Show InChI InChI=1S/C22H29N7O3/c1-31-14-10-13(11-15(12-14)32-2)26-20-18(19(24)30)21-25-8-9-29(21)22(28-20)27-17-7-5-3-4-6-16(17)23/h8-12,16-17,26H,3-7,23H2,1-2H3,(H2,24,30)(H,27,28)/t16-,17?/m1/s1
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Similars
Article
PubMed
n/an/a 1.60n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant Syk (unknown origin)

Bioorg Med Chem Lett 19: 1944-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.049
BindingDB Entry DOI: 10.7270/Q2WM1D98
More data for this
Ligand-Target Pair