BDBM50249392 5-chloro-N-(5-chloropyridin-2-yl)-2-(4-(1-ethyl-4,5-dihydro-1H-imidazol-2-yl)benzamido)benzamide::CHEMBL475186

SMILES: CCN1CCN=C1c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1

InChI Key: InChIKey=ITLJHZYOXMHBHS-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50249392 (5-chloro-N-(5-chloropyridin-2-yl)-2-(4-(1-ethyl-4,...) Show SMILES CCN1CCN=C1c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 |c:5| Show InChI InChI=1S/C24H21Cl2N5O2/c1-2-31-12-11-27-22(31)15-3-5-16(6-4-15)23(32)29-20-9-7-17(25)13-19(20)24(33)30-21-10-8-18(26)14-28-21/h3-10,13-14H,2,11-12H2,1H3,(H,29,32)(H,28,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
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