BDBM50249393 CHEMBL474650::N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-(trifluoromethoxy)benzamide

SMILES: CN(C)C(=N)c1ccc(cc1)C(=O)Nc1ccc(OC(F)(F)F)cc1C(=O)Nc1ccc(Cl)cn1

InChI Key: InChIKey=VRKAWVPHBXFMEM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50249393 (CHEMBL474650 | N-(5-chloropyridin-2-yl)-2-(4-(N,N-...) Show SMILES CN(C)C(=N)c1ccc(cc1)C(=O)Nc1ccc(OC(F)(F)F)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C23H19ClF3N5O3/c1-32(2)20(28)13-3-5-14(6-4-13)21(33)30-18-9-8-16(35-23(25,26)27)11-17(18)22(34)31-19-10-7-15(24)12-29-19/h3-12,28H,1-2H3,(H,30,33)(H,29,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair