BDBM50249755 2-[(5S)-4,4-Bis(4-fluorophenyl)-5-propyl-4,5-dihydro-1H-imidazol-2-yl]-4-pyridinecarbonitrile::CHEMBL490949

SMILES: CCC[C@@H]1NC(=NC1(c1ccc(F)cc1)c1ccc(F)cc1)c1cc(ccn1)C#N

InChI Key: InChIKey=ZYAQGVAAYQRPEP-QFIPXVFZSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249755   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50249755 (2-[(5S)-4,4-Bis(4-fluorophenyl)-5-propyl-4,5-dihyd...) Show SMILES CCC[C@@H]1NC(=NC1(c1ccc(F)cc1)c1ccc(F)cc1)c1cc(ccn1)C#N |r,c:5| Show InChI InChI=1S/C24H20F2N4/c1-2-3-22-24(17-4-8-19(25)9-5-17,18-6-10-20(26)11-7-18)30-23(29-22)21-14-16(15-27)12-13-28-21/h4-14,22H,2-3H2,1H3,(H,29,30)/t22-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cells				J Med Chem 52: 3385-96 (2009) Article DOI: 10.1021/jm900110t BindingDB Entry DOI: 10.7270/Q2DN450G
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50249755 (2-[(5S)-4,4-Bis(4-fluorophenyl)-5-propyl-4,5-dihyd...) Show SMILES CCC[C@@H]1NC(=NC1(c1ccc(F)cc1)c1ccc(F)cc1)c1cc(ccn1)C#N |r,c:5| Show InChI InChI=1S/C24H20F2N4/c1-2-3-22-24(17-4-8-19(25)9-5-17,18-6-10-20(26)11-7-18)30-23(29-22)21-14-16(15-27)12-13-28-21/h4-14,22H,2-3H2,1H3,(H,29,30)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [35S]N-[(4R)-1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin]6-yl]methanesu...				J Med Chem 52: 3385-96 (2009) Article DOI: 10.1021/jm900110t BindingDB Entry DOI: 10.7270/Q2DN450G
					More data for this Ligand-Target Pair