BDBM50250348 3-oxo-olean-12-en-29-oic acid::3-oxoolean-12-en-29-oic acid::CHEMBL491702
SMILES: CC1(C)[C@@H]2CC[C@]3(C)[C@H](CC=C4[C@@H]5C[C@@](C)(CC[C@]5(C)CC[C@@]34C)C(O)=O)[C@@]2(C)CCC1=O
InChI Key: InChIKey=CGZZFWMLSVHLFZ-FUQFICMISA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA polymerase beta (Rattus norvegicus) | BDBM50250348 (3-oxo-olean-12-en-29-oic acid | 3-oxoolean-12-en-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Charlottesville Curated by ChEMBL | Assay Description Inhibition of rat DNA polymerase beta | J Nat Prod 62: 1110-3 (1999) Article DOI: 10.1021/np990104r BindingDB Entry DOI: 10.7270/Q2C8293M | |||||||||||
More data for this Ligand-Target Pair |