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SMILES: OP(O)(=O)C(F)(C(=O)N1CCCCC1)c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F

InChI Key: InChIKey=YKNSTQJGOGNLCR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50250602   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 5


(Homo sapiens (Human))		BDBM50250602
PNG
(CHEMBL4087599)
Show SMILES OP(O)(=O)C(F)(C(=O)N1CCCCC1)c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F
Show InChI InChI=1S/C26H23Cl3F2NO4P/c27-21-15-23(29)22(28)14-18(21)13-17-5-4-6-20(24(17)30)16-7-9-19(10-8-16)26(31,37(34,35)36)25(33)32-11-2-1-3-12-32/h4-10,14-15H,1-3,11-13H2,(H2,34,35,36)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
 3.00E+3n/an/an/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90...

J Med Chem 60: 9299-9319 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01292
BindingDB Entry DOI: 10.7270/Q2NZ8B27
More data for this
Ligand-Target Pair