BDBM50250857 CHEMBL4081625

SMILES: FC(F)(F)C(OC(=O)N1CC(C1)N1CCN(CC1)c1ncccn1)C(F)(F)F

InChI Key: InChIKey=GNGJOXRYUALUAQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50250857   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50250857 (CHEMBL4081625) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)N1CCN(CC1)c1ncccn1)C(F)(F)F Show InChI InChI=1S/C15H17F6N5O2/c16-14(17,18)11(15(19,20)21)28-13(27)26-8-10(9-26)24-4-6-25(7-5-24)12-22-2-1-3-23-12/h1-3,10-11H,4-9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50250857 (CHEMBL4081625) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)N1CCN(CC1)c1ncccn1)C(F)(F)F Show InChI InChI=1S/C15H17F6N5O2/c16-14(17,18)11(15(19,20)21)28-13(27)26-8-10(9-26)24-4-6-25(7-5-24)12-22-2-1-3-23-12/h1-3,10-11H,4-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair