BDBM50251001 CHEMBL457677::Kazinol F

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#6]-[#6]-[#6]-c2ccc(-[#8])cc2-[#8])cc(-[#8])c(-[#8])c1-[#6]\[#6]=[#6](/[#6])-[#6]

InChI Key: InChIKey=PNQQDEFGJPUAGZ-UHFFFAOYSA-N

Data: 3 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50251001   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50251001 (CHEMBL457677 | Kazinol F) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#6]-[#6]-[#6]-c2ccc(-[#8])cc2-[#8])cc(-[#8])c(-[#8])c1-[#6]\[#6]=[#6](/[#6])-[#6] Show InChI InChI=1S/C25H32O4/c1-16(2)8-12-21-19(7-5-6-18-10-11-20(26)15-23(18)27)14-24(28)25(29)22(21)13-9-17(3)4/h8-11,14-15,26-29H,5-7,12-13H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	181	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Gyeongsang National University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase by kinetic based assay				Bioorg Med Chem 17: 35-41 (2008) Article DOI: 10.1016/j.bmc.2008.11.022 BindingDB Entry DOI: 10.7270/Q2GH9HTH
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50251001 (CHEMBL457677 | Kazinol F) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#6]-[#6]-[#6]-c2ccc(-[#8])cc2-[#8])cc(-[#8])c(-[#8])c1-[#6]\[#6]=[#6](/[#6])-[#6] Show InChI InChI=1S/C25H32O4/c1-16(2)8-12-21-19(7-5-6-18-10-11-20(26)15-23(18)27)14-24(28)25(29)22(21)13-9-17(3)4/h8-11,14-15,26-29H,5-7,12-13H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Gyeongsang National University Curated by ChEMBL					Assay Description Inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by Lineweaver-Burk plot based kinetic assay				Bioorg Med Chem 17: 35-41 (2008) Article DOI: 10.1016/j.bmc.2008.11.022 BindingDB Entry DOI: 10.7270/Q2GH9HTH
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50251001 (CHEMBL457677 | Kazinol F) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#6]-[#6]-[#6]-c2ccc(-[#8])cc2-[#8])cc(-[#8])c(-[#8])c1-[#6]\[#6]=[#6](/[#6])-[#6] Show InChI InChI=1S/C25H32O4/c1-16(2)8-12-21-19(7-5-6-18-10-11-20(26)15-23(18)27)14-24(28)25(29)22(21)13-9-17(3)4/h8-11,14-15,26-29H,5-7,12-13H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Gyeongsang National University Curated by ChEMBL					Assay Description Inhibition of diphenolase activity of mushroom tyrosinase using as L-DOPA substrate by Lineweaver-Burk plot based kinetic assay				Bioorg Med Chem 17: 35-41 (2008) Article DOI: 10.1016/j.bmc.2008.11.022 BindingDB Entry DOI: 10.7270/Q2GH9HTH
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50251001 (CHEMBL457677 | Kazinol F) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#6]-[#6]-[#6]-c2ccc(-[#8])cc2-[#8])cc(-[#8])c(-[#8])c1-[#6]\[#6]=[#6](/[#6])-[#6] Show InChI InChI=1S/C25H32O4/c1-16(2)8-12-21-19(7-5-6-18-10-11-20(26)15-23(18)27)14-24(28)25(29)22(21)13-9-17(3)4/h8-11,14-15,26-29H,5-7,12-13H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Gyeongsang National University Curated by ChEMBL					Assay Description Inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate				Bioorg Med Chem 17: 35-41 (2008) Article DOI: 10.1016/j.bmc.2008.11.022 BindingDB Entry DOI: 10.7270/Q2GH9HTH
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50251001 (CHEMBL457677 | Kazinol F) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#6]-[#6]-[#6]-c2ccc(-[#8])cc2-[#8])cc(-[#8])c(-[#8])c1-[#6]\[#6]=[#6](/[#6])-[#6] Show InChI InChI=1S/C25H32O4/c1-16(2)8-12-21-19(7-5-6-18-10-11-20(26)15-23(18)27)14-24(28)25(29)22(21)13-9-17(3)4/h8-11,14-15,26-29H,5-7,12-13H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Gyeongsang National University Curated by ChEMBL					Assay Description Inhibition of diphenolase activity of mushroom tyrosinase using as L-DOPA substrate				Bioorg Med Chem 17: 35-41 (2008) Article DOI: 10.1016/j.bmc.2008.11.022 BindingDB Entry DOI: 10.7270/Q2GH9HTH
					More data for this Ligand-Target Pair